Intensive Insulin Therapy in Severely Burned Pediatric Patients
نویسندگان
چکیده
منابع مشابه
Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial.
RATIONALE Hyperglycemia and insulin resistance have been shown to increase morbidity and mortality in severely burned patients, and glycemic control appears essential to improve clinical outcomes. However, to date no prospective randomized study exists that determines whether intensive insulin therapy is associated with improved post-burn morbidity and mortality. OBJECTIVES To determine wheth...
متن کاملThe use of exenatide in severely burned pediatric patients
INTRODUCTION Intensive insulin treatment (IIT) has been shown to improve outcomes post-burn in severely burnt patients. However, it increases the incidence of hypoglycemia and is associated with risks and complications. We hypothesized that exenatide would decrease plasma glucose levels post-burn to levels similar to those achieved with IIT, and reduce the amount of exogenous insulin administer...
متن کاملTransdermal fluid loss in severely burned patients
INTRODUCTION The skin protects against fluid and electrolyte loss. Burn injury does affect skin integrity and protection against fluid loss is lost. Thus, a systemic dehydration can be provoked by underestimation of fluid loss through burn wounds. PURPOSE We wanted to quantify transdermal fluid loss in burn wounds. METHOD Retrospective study. 40 patients admitted to a specialized burn unit ...
متن کاملIntensive insulin therapy in critically ill patients.
OBJECTIVE To observe the effect of intensive insulin therapy on improving the condition of critically ill patients. METHODS A prospective, randomized, controlled study involving adults receiving mechanical ventilation was performed. On admission, critically ill patients were randomly assigned to receive intensive insulin therapy (infusion of insulin only if the blood glucose level exceeded 6....
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The systemic impact of severe burn injury results in a variety of disorders that require therapeutic intervention. Propranolol, a nonselective β1, β2-adrenergic receptor antagonist, reduces resting heart rate and cardiac work caused by elevated circulating catecholamines. Oxandrolone, a testosterone mimetic, promotes protein synthesis and anabolism to counter muscle wasting. Coadministration of...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2010
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.201002-0190oc